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04/11/2025 - 11:00 Karolien De Bosscher, VIB Center for Medical Biotechnology & UGent Department of Biomolecular Medicine The potential of glucocorticoid receptor crosstalk mechanisms to alleviate inflammation and cancer Host: Bruno Amati Location: IEO Ivory & Silver Room --- Karolien De Bosscher, a molecular biologist, earned her Ph.D. from UGent in 2000. Following postdoctoral research at Cancer Research UK with an EMBO fellowship she returned to Belgium to conduct nuclear receptor research as a postdoctoral fellow of FWO-Vlaanderen. In 2013, she secured a research professorship, combining research and teaching at UGent. From 2019 onwards, she is a full professor at UGent and principal investigator at the VIB Center for Medical Biotechnology. Throughout her career, Dr. De Bosscher focused on unraveling nuclear receptor intricacies, exploring anti-inflammatory and anti-cancer mechanisms. Her team investigates selective glucocorticoid receptor modulation, metabolic actions of nuclear receptors, and crosstalk mechanisms in hematological cancers. Dr. De Bosscher's lab decodes how nuclear receptors transduce signals, aiming to innovate receptor-targeting strategies for enhanced therapeutic benefits. The team develops cell-based tools to capture nuclear receptors' complexity, contributing to drug discovery platforms.
November 04, 2025
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In the past 20 years since DEO foundation, many scientists have started their career and matured professionally in the department. This has created a large community of scientists that, even though are now working in different institutes in the world, keep pleasant memories and a strong tie with their experience in IEO. In 2018, DEO organized the first Alumni meeting, where 50 ex-PhD students, post-doctoral fellows and Group Leaders of IEO, now Principal Investigators or Institute Directors worldwide, met and renewed their pleasure to interact and discuss science.
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The Italian Government offers tax payers the opportunity of devolving 0.5% of their taxes to not for profit organizations. This option is known as the “Cinque per mille” (5x1000).
On the occasion of the payment of your income tax return by 730, or CUD in Italy, you can sign up to donate 5x1000 of your tax in favor of the European Institute of Oncology (IEO), thus sustaining research, innovation and cure.