Molecular bases and functional implications of cellular heterogeneity in pancreatic cancer (Ref. 2024-07-GN/62)

We are recruiting a postdoctoral scientist to investigate the molecular bases and therapeutic implications of cellular heterogeneity in pancreatic cancer.

 

The project is based on the use of complementary cutting-edge genomics and proteomics coupled with functional genomics technologies. It involves tight interactions with other members of a team working on pancreatic cancer and with the broad community of experimental and computational biologists of the IFOM-IEO Campus in Milan.

 

The applicants should hold a PhD and have expertise in research areas related to molecular biology, genomics and/or proteomics.

 

Interested candidates are encouraged to submit their curriculum vitae, a short presentation of their research interests and the name of two referees to Gioacchino Natoli ([email protected]).

 

Deadline for applications: November 15, 2024

 

Group website

https://www.research.ieo.it/research-and-technology/principal-investigators/gioacchino-natoli/

 

Selected recent publications from the lab

Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer (Di Chiaro P…Natoli G) Cancer Cell. 2024 Apr 8;42(4):662-681 PMID: 38518775

Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer (Cortesi A…Natoli G) Science Advances. 2024 Mar 29;10(13):eadk5386. PMID: 38536927

Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide (Russo M…Natoli G) Molecular Cell Mar 7;84(5):967-980.e10. PMID: 38242130

 

Posted on 22nd July 2024