Imaging Unit
Simona Rodighiero
Unit Coordinator
[email protected] | |
Telephone | +390294375026 |
Location |
Building 1
Floor Ground Via Adamello 16, Milano |
The Imaging Unit (IU) supports DEO scientific groups by offering cutting-edge optical imaging platforms and developing tailored imaging protocols and image analysis pipelines as per specific requirements.
More specifically, the IU activity include:
- Conducting mandatory microscope training sessions to facilitate direct access to all IU microscopes
- Providing image analysis support, including integration of machine learning into image analysis
- Offering consulting services for sample preparation in optical microscopy experiments
- Offering direct support and troubleshooting at the microscopes
- Managing departmental imaging reagents
- Teaching (SEMM PhD school and Master in Biomedical Omics of the University of Milan)
Additionally, IU staff actively participates in research collaborations with various research groups
Tools we use:
- image analysis: Fiji/ImageJ, QuPath, ArivisVision 4D, NIS-Elements, Huygens, Python
- data analysis: R, Python
Most Relevant Publications
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Hayatigolkhatmi K, Soriani C, Soda E, Ceccacci E, El Menna O, Peri S, Negrelli I, Bertolini G, Franchi GM, Carbone R, Minucci S, Rodighiero S.
Automated workflow for the cell cycle analysis of (non-)adherent cells using a machine learning approach
Elife, 2024
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Di Chiaro P, Nacci L, Arco F, Brandini S, Polletti S, Palamidessi A, Donati B, Soriani C, Gualdrini F, Frigè G, Mazzarella L, Ciarrocchi A, Zerbi A, Spaggiari P, Scita G, Rodighiero S, Barozzi I, Diaferia GR, Natoli G
Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer.
Cancer Cell, 2024
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Mulè P, Fernandez-Perez D, Amato S, Manganaro D, Oldani P, Brandini S, Diaferia G, Cuomo A, Recordati C, Soriani C, Dondi A, Zanotti M, Rustichelli S, Bisso A, Pece S, Rodighiero S, Natoli G, Amati B, Ferrari KJ, Chiacchiera F, Pasini D
WNT Oncogenic Transcription Requires MYC Suppression of Lysosomal Activity and EPCAM Stabilization in Gastric Tumours.
Gastroenterology, 2024
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Russo M, Piccolo V, Polizzese D, Prosperini E, Borriero C, Polletti S, Bedin F, Marenda M, Michieletto D, Mandana GM, Rodighiero S, Cuomo A, Natoli G
Restrictor synergizes with Symplekin and PNUTS to terminate extragenic transcription.
Genes Dev, 2023