Diagnostics and biomarkers
PETsign - A PET-surrogate multigene signature for breast cancer prognosis
Innovative multigene signature serving as FDG-PET surrogate able to predict tumor metabolic profiles and disease outcome in breast cancer patients
Download PDF Brochure
PROSIBLAD - PRecision Oncology Signature for Invasive BLADder Cancer
Innovative multigene signature designed to identify NMIBC patients at high-risk of progression and recurrence, providing a powerful tool for precise clinical decision-making
Download PDF Brochure
LGLBioTrack: Novel Biomarkers Tracking T-LGLL progression and treatment
Innovative method developed to predict the progression of T-cell large granular lymphocytic leukemia based on the expression of specific biomarkers
Download PDF Brochure
L1-ΔTM: New circulating biomarker of tumor angiogenesis
Novel biomarker for the non-invasive diagnosis and therapeutic monitoring of cancer patients
Download PDF BrochureDrug discovery
EPIgenetic marks for unbiased, high content functional profiling of clinical KINase inhibitors
Cutting-edge experimental and analytic platform to functionally profile the effects of clinical kinase inhibitors in living cells, enabling drug repurposing and guiding early clinical decision-making
Download PDF Brochure
Biologicals
FLachImmune - Innovative peptide-based approach to enhance anti-tumor immune response
Bacterial-derived peptides with a crucial role in priming antitumor immunity and enhancing cancer immunotherapy response by mimicking tumor-associated antigens
Download PDF Brochure
iRASP: a novel platform to design efficacious cancer targeted immunotherapies
New therapeutic antibodies for the treatment of intractable tumors
Download PDF Brochure Watch the VideoPitch
Therapeutic Small Molecules
Epigenetic drugs for the treatment of viral infections
New potential therapeutics for SARS-CoV-2-infected patients
Download PDF Brochure
Therapeutic strategy against cancer escaping metabolic inhibitors
New anti-cancer metabolic therapy based on PP2A activator molecules
Download PDF Brochure
Histone demethylases to ameliorate core symptoms in rare subtypes of Autism Spectrum Disorder
Novel pharmacological agents for the treatment of core symptoms of rare subtypes of Autism Spectrum Disorders
Download PDF Brochure Watch the VideoPitch
Research tools
Monoclonal Antibodies
|
Target protein |
Clone(s) |
Applications |
Reactivity |
Group leader |
References |
Supplier |
|
Cmt2 |
E29-19-14 |
WB, IF, IP |
|
Andrea Musacchio |
|
EMD Millipore |
|
DEPDC1B (DEP domain-containing protein 1B) |
CH18-2-9 |
WB, IP |
human, mouse |
Pier Paolo Di Fiore |
|
|
|
DLG1 (Disks large homolog 1) |
B7-1 |
IF |
Human |
Pier Giuseppe Pelicci |
|
|
|
Dsn1 |
RD36-1 |
WB, IF, IP |
Human |
Andrea Musacchio |
|
EMD Millipore |
|
NP95 (E3 ubiquitin-protein ligase UHRF1) |
BF18-11 |
WB, IP, IF |
mouse |
Pier Paolo Di Fiore |
|
|
|
EPS15 (Epidermal growth factor receptor substrate 15) |
15-3T |
WB, IP, IF |
human, mouse |
Pier Paolo Di Fiore |
|
|
|
HDAC1 pSer406 |
BT-15 |
IF, WB, IP |
Human, Zebrafish, Mouse |
Susanna Chiocca |
Segrè CV et al., MAbs 2015 |
EMD Millipore; Biolegend |
|
Mad1 (mitotic arrest deficient 2) |
BB3-8 |
WB, IF, IP |
Human |
Andrea Musacchio |
Screpanti E et al., Curr Biol. 2011; Santaguida S et al., J Cell Biol 2010; De Antoni A et al., Curr Biol 2005; Steensgaard et al., EMBO Rep 2004; DeLuca et al., Curr Biol 2003 |
EMD Millipore |
|
Mad2 (mitotic arrest deficient 2) |
AS55-A12 |
WB, IF, IP |
Human |
Andrea Musacchio |
Screpanti E et al., Curr Biol. 2011; Santaguida S et al., J Cell Biol 2010; De Antoni A et al., Curr Biol 2005; Steensgaard et al., EMBO Rep 2004; DeLuca et al., Curr Biol 2003 |
EMD Millipore |
|
Notch1 (Neurogenic locus notch homolog protein 1) |
BB25-15-2; 18G12-1 |
WB |
Human |
Pier Paolo Di Fiore |
|
|
|
NUDCD1 (NudC domain-containing protein 1) |
AR55-1-4 |
WB, IF, IP, IHC paraffin |
human |
Pier Paolo Di Fiore |
|
|
|
NuMA1 (Nuclear mitotic apparatus protein 1) |
AD6-1 |
IF,WB |
Human, mouse |
Marina Mapelli |
Gallini S et al., Current Biology 2016; Carminati M et al., NSMB 2016; Pirovano L et al., Nat. Comm 2019 |
EMD Millipore |
|
NUMB (Protein numb homolog) |
AB21-39-25-15; AA19-2; AP35-A1 |
WB, IHC, IF |
human, mouse |
Pier Paolo Di Fiore |
Colaluca I et al., Nature 2008 |
|
|
p66shc |
BG8-SU1 |
WB, IP, IF |
human, mouse |
Pier Giuseppe Pelicci |
Orsini et al., JBC 2004 |
|
|
Protein FAM91A1 |
BL5-4; EI1-3; P1-84; P1-65 |
WB, IP, IF, IHC paraffin |
human, mouse |
Pier Paolo Di Fiore |
Nicassio F et al., J Clin Invest 2005 |
|
|
RAI (SHC C) |
IF15-E2 |
IHC, WB, IP |
human, mouse |
Giuliana Pelicci |
Villanacci V et al., Neurogastroenterol Motil 2008 |
EMD Millipore |
|
RaLP (RAI-like protein) |
AW47-10-21; AW47-10-5; AI22-20-8; AI22-20-15 |
WB |
human, mouse |
Luisa Lanfrancone |
|
|
|
RN-tre |
15-6-11; 15-B |
WB, IP, IF |
human |
Pier Paolo Di Fiore |
Lanzetti L et al., Nature 2004 |
|
|
SCC-112 (Sister chromatid cohesion protein PDS5 homolog A) |
AF5-21-7 |
WB, IP, IF, IHC paraffin |
human, mouse |
Pier Paolo Di Fiore |
|
|
|
SMU1 (WD40 repeat-containing protein SMU1) |
AQ26-ED8-22-11 |
WB, IF, IHC paraffin |
human |
Pier Paolo Di Fiore |
|
|
|
USP3 (Ubiquitin carboxyl-terminal hydrolase 3) |
AE9-12-1 |
WB, IP |
human, mouse |
Pier Paolo Di Fiore |
Nicassio F et al; Curr Biol 2007 |
|
For more information please contact IEO-TT
Download IEO Mabs CataloguePreclinical models
Please contact IEO-TT
Research programs
Please contact IEO-TT