IEO PATENT PORTFOLIO
Therapy
SMALL MOLECULES
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Therapeutic use of PCYOX1 inhibitors |
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Use of a molecule capable of inhibiting PCYOX1 for use in the treatment and prevention of cancer and metastases. |
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Application n. PCT/EP2023/055604 |
Priority Date 04/03/2022 |
Main Inventors Saverio Minucci Isabella Pallavicini |
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Molecules for use in the treatment of viral infections |
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Epigenetic drugs for use in the treatment and/or prevention of a viral infection and method to screen a therapeutic treatment of a viral infection |
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Application n. IT-102020000007873 |
Priority Date 14/04/2020 |
Main Inventor(s) Luca Mazzarella Saverio Minucci Pier Giuseppe Pelicci |
Status Available for partnering |
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Compounds and composition for the treatment of tumors |
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Compounds blocking homologous recombination (HR) DNA repairing mechanism by disrupting Rad51-BRCA2 interaction |
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Application n. PCT/IB2020/061825 |
Priority Date 11/12/2019 |
Main Inventors Saverio Minucci Giuseppe Pelicci |
Status For more information |
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Hect E3 ligase NEDD4 inhibitors and uses thereof |
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New E3 ubiquitin-ligase NEDD4 inhibitor molecules and their use for the treatment of oncological and infectious pathologies |
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Application n. PCT/EP2020/065372 |
Priority Date 03/06/2019 |
Main Inventor(s) Sebastiano Pasqualato |
Status For more information |
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Therapy and diagnosis of disease characterized by alterations in the DNA damage response |
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Activators of PP2A phosphatase, their use for the treatment of oncological pathologies and method to identify eligible patients for PP2A activators-based therapy. |
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Application n. PCT/EP2018/063257 |
Priority Date 19/05/2017 |
Main Inventor(s) Saverio Minucci |
Status Available for partnering |
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Reprogramming-based models of neurodevelopmental disorders and uses thereof |
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Neuronal cell models based on reprogrammed stem cells from patients with autism spectrum disorders, methods of obtaining them and use of LSD1 inhibitors for their treatment. |
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Application n. PCT/EP2015/077659 |
Priority Date 26/11/2014 |
Main Inventor(s) Giuseppe Testa |
Status Available for partnering |
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New LSD1 inhibitor molecules in oncology (7 patent families) |
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New small molecules inhibiting LSD1 enzyme for the treatment of oncological diseases alone or in combination with other therapeutic agents |
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Application n. PCT/EP2011/055990 PCT/EP2013/075409 PCT/EP2015/062037 PCT/IB2015/001953 PCT/EP2017/062009 PCT/EP2018/060637
PCT/EP2018/072319 |
Priority Date 20/04/2010 05/12/2012 30/05/2014 05/09/2014 18/05/2016 26/04/2017
18/08/2017 |
Main Inventor(s) Saverio Minucci Mario Varasi Mario Varasi Mario Varasi Mario Varasi Saverio Minucci Pier Giuseppe Pelicci Mario Varasi |
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Biologicals
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Flagellin-related peptides and uses thereof |
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Ehancement of antitumor immunity with flagellin-based peptides in melanoma patients undergoing immune checkpoint inhibitor’s therapy |
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Application n. EP24164184.4 |
Priority Date 18/03/2024 30/07/2024 |
Main Inventors Luigi Nezi
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Status For more information |
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Engineered transposase and uses thereof |
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An engineered transposase comprising a transposase operably linked to a polypeptide that binds to a component of heterochromatin |
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Application n. PCT/EP2022/052915 |
Priority Date 05/02/2021 |
Main Inventors Sebastiano Pasqualato |
Status For more information |
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Antibodies anti-tumor associated antigens and method for obtaining them New tumor-specific antibodies, method for obtaining them and their use in the treatment of oncological pathologies. |
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Application n. PCT/EP2019/066217 |
Priority Date 19/06/2018 |
Main Inventor(s) Pier Giuseppe Pelicci |
Status Available for partnering |
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Postbiotic-based composition for treatment of ocular inflammation Metabolic products of Lactobacillus Paracasei for the treatment of conjunctivitis |
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Application n. PCT/EP2017/069681 |
Priority Date 03/08/2016 |
Main Inventor(s) Maria Rescigno |
Status Partnered |
Methods and biomarkers
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Method for prognosis of bladder cancer |
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A multigene predictor of risk of muscle-invasion for personalized management of non-muscle- invasive bladder cancer (NMIBC) patients. |
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Application n. EP24191940.6 |
Priority Date 31/07/2024 |
Main Inventors Salvatore Pece Daniela Tosoni Giuseppe Renne |
Status For more information |
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Method for prognosis of breast cancer |
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A PET-surrogate signature that interrogates the metabolic status of breast cancers and independently prognosticates bad clinical outcome. |
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Application n. EP24165583.6 |
Priority Date 22/03/2024 |
Main Inventors Pier Paolo DI Fiore Stefano Confalonieri Bronislava Matoskova |
Status For more information |
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A novel isoform of the cell-surface adhesion molecule L1 having high angiogenic activity |
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New soluble isoform of L1 adhesion protein and related diagnostic kit for the detection and monitoring of oncological pathologies |
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Application n. IT n. 102018000007726 |
Priority Date 01/08/2018 |
Main Inventor(s) Ugo Cavallaro |
Status Available for partnering |
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Use of the expression of specific genes for the prognosis of patients with triple negative breast cancer |
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Use of the expression of specific genes for prognostic evaluation in patients with triple negative breast cancer and who have received neoadjuvant chemotherapy |
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Application n. PCT/EP2017/066533 |
Priority Date 01/07/2016 |
Main Inventor(s) Giuseppe Curigliano |
Status For more information |
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Methods and kits comprising gene signatures for stratifying breast cancer patients |
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Prognostic molecular signature for the evaluation of risk of relapse in patients with ER positive and HER2 negative breast cancer |
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Application n. PCT/EP2017/064937 |
Priority Date 20/06/2016 |
Main Inventors Pier Paolo DI Fiore Salvatore Pece |
Status Partnered |
Medical device
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Multifunctional hybrid cellulose nanocrystals-gold nanoplatform and use thereof in medicine |
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High-performance, high-quality nanotechnology for applications in the field of precision nanomedicine |
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Application n. PCT/IB2023/055515 |
Priority Date 31/05/2022 |
Main Inventors Saverio Minucci Cristina Garibaldi Roberto Orecchia |
Status |