Simona Rodighiero
[email protected] | |
Telephone | +390294375026 |
Location | Building 1 Floor Ground Via Adamello 16, Milano |
Member of
In 1999, I earned a Master's in Biological Sciences, specializing in electrophysiology, from the University of Milano. In 2004, I completed a Ph.D., studying anion currents' regulation of cell volume. My expertise expanded to laser scanning confocal microscopy and Fluorescence Resonance Energy Transfer (FRET).
From 2005 to 2009, I led the CIMaINa confocal microscopy unit. At Fondazione Filarete (2009 onward), as Staff Technologist and Optical Microscopy Coordinator, I worked on diverse projects like nanoparticle internalization, cell adhesion, protein-protein interactions, and correlative microscopy.
Joining ETH Zürich in 2015, I became a Staff Scientist, leading the Microscopy Training Program. Managing four electron microscopes, I trained students in electron, optical, and correlative microscopy. The organized courses, part of the ETHZ course catalogue, covered both basic and advanced microscopy techniques.
In 2018, I joined the European Institute of Oncology, overseeing the Imaging Unit. Collaborating with DEO researchers, I conduct optical microscopy experiments using various imaging modes on diverse samples, including human tissues. I actively contribute to microscopy and image analysis courses at the European School for Molecular Medicine and provide hands-on training for UNIMI master’s students, underlining my commitment to imparting technical skills to the next generation of scientists.
Most Relevant Publications
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Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity.
Cell Metab, 2023
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Targeting mitochondrial respiration and the BCL2 family in high-grade MYC-associated B-cell lymphoma.
Mol Oncol, 2022
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BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation.
Mol Cell, 2021
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Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells.
J Exp Med, 2020