
Stefano Freddi
[email protected] | |
Telephone | 45164 |
Location |
Building 13
Floor 2nd Via Adamello 16, Milano |
Member of
Dr. Stefano Freddi is a physicist in Sara Sigismund’s group at the IEO, who supports researchers in the magical universe of microscopy, cytometry and data analysis.
He obtained a Master Degree in Biophysics in 2008 and then he was awarded a PhD in Physics at the University of Milano Bicocca. He has gained an extensive background in development and characterization of nanoparticles and he has a broad experience in spectroscopic and imaging techniques including fluorescence correlation spectroscopy, two-photon microscopy and in-vivo and ex-vivo microscopy.
Dr. Freddi joined the Molecular Medicine for Care (MMC) program, directed by Prof. Pier Paolo Di Fiore in 2013. Since then, he has improved his abilities in the creation of codes for image analysis, data management and the development models applied to biology. He also successfully gained new skills in cytometry analysis using FACS and biostatistical analysis of PCR and immunohistochemistry data generated from the screening of large cohorts of patients.
In recent years, Dr. Freddi has supported the research activities of the Molecular Pathology Unit and the Novel Diagnostics Program. Currently, he works in the group of Organelle Communication, Trafficking and Cancer under the supervision of Dr. Sara Sigismund, developing algorithms for the analysis of high-resolution fluorescence and electron microscopy images, in the context of endocytic mechanisms and interorganelle communication.
Most Relevant Publications
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A tripartite organelle platform links growth factor receptor signaling to mitochondrial metabolism.
Nat Commun, 2024
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Loss of NUMB drives aggressive bladder cancer via a RHOA/ROCK/YAP signaling axis.
Nat Commun, 2024
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L1CAM promotes ovarian cancer stemness and tumor initiation via FGFR1/SRC/STAT3 signaling.
Exp Clin Cancer Res, 2021
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A molecular thermometer for nanoparticles for optical hyperthermia.
Nano Lett, 2013